ACAD108041

Investigating antidepressant mechanisms on astrocytes

A postdoctoral position is available in Glia and Psychiatry Lab led by Dr Valentina Mosienko at the University of Bristol (Glia and Psychiatry Lab - Mosienko). We are looking for an enthusiastic, curious and driven individual who will join the team to investigate mechanisms of antidepressants on astrocytes.

You will work on topics across Glia Biology, Cell signalling and metabolism and Psychiatry using a wide range of methods including cell-type specific manipulation of gene expression in vitro using viral approach, life-cell imaging, metabolic assay, and molecular and cellular biology techniques such as immunohistochemistry, in situ hybridisation and RT-qPCR.

You will be embed within a multidisciplinary and dynamic team of researchers and vibrant Neuroscience community at the University of Bristol. You will have ample opportunities to grow in areas of molecular and cellular neuroscience, as well as to collaborate with bioinformaticians, present your work at conferences, and contribute to publishing original research and review papers

What will you be doing?

Primary research responsibilities will include working with various cultures in sterile environment, running and analysing live-cell imaging experiments and various assays aimed to assess cell metabolism. You will also be involved in day-to-day project management and supporting training and supervision of postgraduate and undergraduate lab members. You will be encouraged to participate in outreach activities and teaching.

You hold a PhD (or be working towards one) in Neuroscience or related disciplines and have prior research experience in the area of cellular and molecular neuroscience. Competitive candidates will have experience working with primary, human and iPSCs cell cultures to evaluate changes in intracellular messengers and cell metabolism. You will be ideal for this role if you are well-organised, enthusiastic about working with cells and animals in the field of Psychoneuroimmunology, and eager to learn new techniques and to work as part of a group.