Higher Scientific Officer - Biology, Target Validation and Genome Stability Group

Under the guidance of Prof Joanna Loizou, we are seeking to recruit a Higher Scientific Officer to join the Target Validation and Genome Stability group within the to carry out lab-based cell biology research focused on potential therapeutic targets in cancer., The , led by Prof Joanna Loizou, focuses on identifying vulnerabilities in the DNA damage response to generate pre-clinical information that can lead to the identification of novel targets for drug discovery programmes. The ICR has established a that will accelerate the translation of ICR and collaborator research into drug discovery programmes. The Centre will deliver bespoke, hypothesis-driven data packages to support decision-making for launch of drug discovery projects. The Centre's dedicated resources, including biology, functional genomics, assay sciences, chemistry, and bioinformatics teams, will support joint project teams that combine the deep biological and therapeutic knowledge of ICR investigators with the validation and technical expertise of drug discovery scientists. Scientists in the Centre for Target Validation will work closely with colleagues in the ICR's to exploit emerging technology and protein degradation tools for robust target validation experiments. The Centre for Target Validation will serve as a hub, connecting researchers to expertise and resources that will validate and streamline robust, targets into drug discovery programmes in the ICR's Centre for Cancer Drug Discovery or into collaborative programmes with external commercial therapy discovery partners. What we offer

• A dynamic and supportive research environment
• Access to state-of-the-art facilities and professional development opportunities
• Collaboration with leading researchers in the field
• Competitive salary and pension
We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Prof Joanna Loizou via Email on . About The Institute of Cancer Research Why work for us? As a member of staff, you'll have exclusive access to a range of . The ICR is committed to supporting overseas applicants applying for roles, here to find out further information. The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found . We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.


• At least a Masters level qualification in Cell Biology or an aligned subject (PhD in Cell Biology or an aligned subject is desirable)
• Knowledge of cancer biology
• Knowledge of experimental approaches to therapeutic target validation in cancer
• Skills in cell biology techniques used for target validation
• Expertise in a range of biology readouts used for screening and biomarker detection
• Experience working in lab-based cell biology (can include PhD)