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Senior Laboratory Operations Technician

ANGLE plc

Senior Laboratory Operations Technician

Salary Not Specified

ANGLE plc, Guildford

  • Full time
  • Permanent
  • Onsite working

Posted today, 29 Sep | Get your application in now to be one of the first to apply.

Closing date: Closing date not specified

job Ref: 0ae4647054e24be3971590d0a59e04e4

Full Job Description

  • Responsible for quality and regulatory compliance of work undertaken.
  • Support in document writing; updating and reviewing current SOP's and WI's procedures.
  • Assisting in laboratory document monitoring tasks including collection, organisation and revision of documents.
  • Contribute to the smooth running of laboratory facility; cleaning laboratory/equipment as required.
  • Complete stock checks, process orders and handle Internal laboratory goods to ensure all required stock is maintained at the correct levels.
  • Formulate buffers and prepare various reagents for the laboratory in accordance with laboratory QMS.
  • Handle hazardous materials, reagents, chemicals and compressed gases in a safe manner in accordance with laboratory policies and procedures.
  • Ensure all consumables and reagents are labelled correctly in accordance with the laboratory Quality Management System (QMS).
  • Arrange for equipment to be calibrated and/or serviced only when support is required within the team. Remaining a back-up for supporting the correct management of defective instruments, including carrying out instrument acceptance tests and maintaining associated records within the laboratory QMS. Ensure equipment is labelled correctly in accordance with laboratory QMS.
  • Support in organising in house calibration or checks for laboratory equipment when required.
  • Support all aspects of Laboratory Management in a variety of tasks both in and out of the laboratory as and when required by line manager; to include but not limited to laboratory administration and operations support.
  • Assist in communication with suppliers and service providers.
  • Contribute to weekly maintenance Parsortix instruments in accordance with laboratory SOPs.
  • Work in accordance with laboratory Standard Operating Procedures (SOP's), ensuring adherence to Health and Safety standards in the laboratory areas, as well as other laboratory standards.
  • Supporting the Laboratory Supervisor in the training of other staff
  • Undertake additional ad-hoc tasks as required.

    'A' Levels and proven, track-record of relevant laboratory experience or BSc in a relevant subject
  • Experience of working to strict quality standards such as ISO9001 or preferably ISO13485 would be a significant advantage
  • Organisational skills and the ability to follow agreed procedures are essential
  • Demonstrated ability to manage teams and prioritize tasks in complex projects
  • Manage and deliver production to agreed timetables and according to defined instructions
  • Strong team player with excellent communication skills, work ethic and attention to detail
  • Good report writing skills, with the ability to communicate results to technical and non-technical staff
  • Strong verbal and written communication skills
  • Ability to multitask and prioritise to meet deadlines
  • Ability to work both independently with minimal supervision as well as in a team environment
  • Continuous learner with a keen appetite for cross-disciplinary work
  • Entrepreneurial thinking and work ethic
  • An eye for detail and commitment to high-quality data
  • A flexible, can-do approach to the requirements of the job

    ANGLE is a world leading liquid biopsy company with sample-to-answer solutions. ANGLE's proven patent protected circulating tumor cell (CTC) harvesting technology is known as the Parsortix® system.
    • ANGLE's Parsortix® system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. The Parsortix system enables a liquid biopsy (a simple blood test) to be used to provide the circulating metastatic breast cancer cells to the user in a format suitable for multiple types of downstream analyses. The system is based on a microfluidic device that captures cells based on a combination of their size and compressibility. The system is epitope independent and can capture all phenotypes of CTCs (epithelial, mesenchymal and EMTing CTCs) as well as CTC clusters in a viable form (alive). CTCs harvested from the system enable a complete picture of a cancer to be seen; as being an intact cell they allow DNA, RNA and protein analysis as well as cytological and morphological examination and may provide comparable analysis to a tissue biopsy in metastatic breast cancer. Because CTC analysis is a non-invasive process, unlike tissue biopsy, it can be repeated as often as needed. This is important because cancer develops and changes over time and there is a clear medical need for up-to-date information on the status of a patient's tumor. In addition, the live CTCs harvested by the Parsortix system can be cultured, which offers the potential for testing tumor response to drugs outside the patient., At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

    Due to the nature of the role, our requirement is for this position to be Guildford-based, office hours, five days per week. As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package. Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.