158 Scientific jobs in Carterton, Oxfordshire

As a Post Doctoral Researcher at the Franklin, you will bring scientific knowledge and skills to deliver a specific research project and/or you will bring independent, creative science, or specific skills to a team delivering a project or program. Through this work, you will build scientific independence, develop new science and leadership skills, and establish a growing reputation externally. If you are a creative scientist that wants to explore novel venues on quantitative imaging biology, then join us. Our lab is interested in Molecular Organisation of Cell Interfaces in the epithelial tissue and in pathology of intestinal diseases. We use super-resolution STED microscopy in combination with gut organoids, biophysics and chemical biology to uncover how epithelial cells organise in space and time under different physico-chemical environments to drive self-organisation processes that shape mesoscale structures enabling tissue function. To that end, we generate high amount of complex data across scales from molecules to mesoscale structures. Our interdisciplinary team includes biology, chemistry and physics. Your role will be to lead a research project focused on quantitative imaging of epithelial cell biology and biophysics. Moreover, support and develop novel workflows of bioimaging analysis to quantify advanced imaging data generated by super-resolution STED microscopy, FLIM, FRET and FCS. You will collaborate with other research institutions including the University of Oxford where we are also based., Your primary task will be to lead a project on quantitative imaging biology. You will develop novel ways of analysing complex data (e.g. 3D volumetric STED) that will enable wider scientific discoveries and advance our understanding of biology. You will also develop novel pipelines of generating quantitative bioimaging data using various optics and electronic tools. We encourage applicants with a broad experimental-analytical interest, as the job holder will contribute both to the development of new methods and their application to investigate the organisation and dynamics of cell interfaces. As a Post Doctoral Researcher, you will also:

• Plan and conduct experiments, analyse and interpret results and supervised delivery of outputs (e.g., research reports, patent applications) in a scientific/technology area of interest.
• Work within a project team, contributing to wider projects around key Challenges.
• Lead major contributions to research outputs including papers, patents and both internal and external presentations.
• Support and develop others including day-to-day supervision of students or visitors in areas related to own research.
• Enhance your research through collaboration with other researchers and make active contributions to exchanging of ideas through your own network.
• Understand, interpret, create and communicate appropriately within a research context.
• Develop search and discovery skills and techniques.
• Be supervised by a Scientist/Senior Scientist in delivery of outputs, either in the context of a project or Challenge or as an early career development fellow.
Before submitting your application, please ensure you read the Job Information Pack for full details of this role on our website.

Candidates must hold a PhD in cell biology, biophysics, physics, mathematics or computer science along with experience in advance quantitative microscopy analysis. We are looking for a colleague with strong organisational and communication skills, with demonstrated laboratory experience. Experience with formulating research questions and devising strategies to address these questions would aid the individual selected for this role. We expect you to lead publications, contribute to research grant writing, collaborate with other members of the lab towards knowledge advancement. This post would be ideal for a candidate who has developed a strong background on bioimaging analysis, quantitative biology or biophysics and would like to lead a project developing novel quantitative imaging pipelines and who would like to gain further experience in cutting edge techniques including super-resolution imaging, condensate biology and cell adhesion in epithelia tissue., Whilst the role is a Postdoctoral Research level and requires candidates to hold a PhD/DPhil (or equivalent), we may consider candidates who are close to completion of their PhD/DPhil qualification, in which case the initial appointment will be made at £36,500 per annum (to be increased on completion of the PhD/DPhil qualification).