We are looking for a post-doctoral research associate to join the Dr Owen Peters Lab in the School of Biosciences and UK Dementia Research Institute at Cardiff University, working in close collaboration with Dr Mariah Lelos, Prof Emma Kidd and Dr Gaynor Smith. In this role, you will:

Lead a Motor Neurone Disease Association-funded research project to assess the contribution of cGAS-STING immune signalling in Amyotrophic Lateral Sclerosis (ALS);
Use state of the art in vitro and in vivo model systems to explore roles for mitochondria dysfunction and cGAS-STING signalling in ageing microglia in ALS. In collaboration with the King's College London Neurodegenerative Diseases Brain Bank, you will translate data from model systems to human post-mortem tissues;
You will have opportunities to develop your research skills, collaborate with an interdisciplinary team of researchers working in translational neuroscience, develop skills in data analysis, manuscript preparation and presentation at research meetings.
Are an enthusiastic and ambitious PDRA candidate with a drive to work in ALS and neurodegeneration-focused research;
Are excited to lead a collaborative project, and contribute to the wider objectives of a translational research team;
Have research experience working in iPSC in vitro models (microglia, neurons), confocal microscopy and/or post-mortem human tissue and molecular biology, with a research interest in ALS, neurodegenerative disease and/or roles of innate immune signalling in mammalian systems.