Biophysics Group leader

We are looking for an exceptional Group Leader, someone with deep knowledge and expertise in biophysics with a passion and talent for their implement to drive drug discovery projects forward. We are particularly interested in individuals with experience in both small molecule and antibody drug discovery, and have worked in close synergy with structural scientists. As a Group Leader, your motivation and forward-thinking approach will be key. You will be tasked with developing, optimising, and validating biophysical assays to deliver project decision-making data swiftly and potentially at scale. Your expertise will guide programs to their choice of technologies, you will be involved in the design of assay cascades and collaborate with program teams to tackle the critical challenges in hit identification, lead optimisation, and candidate selection. This role is primarily lab-based but combines the potential for management responsibilities within and beyond biophysical sciences, providing a platform for continuous learning and growth. You will help form and deliver our department's scientific strategy, working with other members of our global leadership team. You'll be expected to stay abreast of the latest scientific developments in biophysics, evaluate new technologies, and spot opportunities for innovation to shape the future of drug discovery. In our team-oriented environment, you'll have the chance to apply your talents and make a significant impact on a wide variety of therapeutic projects through close collaboration with others. In this role you will:

• Execute biophysical assay development, validation, screening, interpret results, and plan and recommend next steps in a timely manner to solve scientific issues.
• Oversee portfolio of biophysical activities within Stevenage SBS department, including resource allocation, project strategy and integration within a global team.
• Build and maintain a network of cross line interactions to ensure alignment within projects and within technologies that bridge departments as well as maintaining up-to-date knowledge of advancements in the field of biophysics and incorporate this knowledge into current and future research initiatives.
• Author high-quality technical reports and publications with scientifically supported conclusions and recommendations.
• Lead and mentor biophysical scientists fostering a collaborative and productive work environment.
• Contribute to and develop strategic plans for biophysics within the department and in the wider organization., We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
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• Extensive experience in biophysics, both in academic and industrial settings. This may include proficiency in techniques such as SPR, thermal shift, NMR, and mass spectrometry.
• Comprehensive knowledge and practical application of biophysical techniques in medicine discovery programs. In particular for Fragment-Based Drug Discovery (FBDD), hit qualification, and mode-of-action characterisation.
• A proven track record of innovation, specifically in the integration of new biophysical methods into drug discovery processes.
• Exceptional communication skills, with the ability to summarize and contextualize scientific data for project impact. This also includes excellent organizational skills.
• Team player, capable of navigating complex situations, whether they are scientific, logistic, or organizational, and driving success.
• Previous experience in a position of accountability that has influenced others, such as management, project leadership, safety, etc.
Preferred Qualifications & Skills: Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
• Line and project leadership experience.
• Data skills, including scripting and programming.
• Experience working across multiple drug modalities e.g. small molecule, antibody, vaccines, oligonucleotides.
• Experience working with challenging targets such as membrane protein.
• Understanding of associated disciplines such as structural biology and biochemical assay development.
  
  The UK Structural & Biophysical Sciences (SBS) group is a global multi-disciplinary department within GSK R&D that provides molecular insights into drug discovery for small molecule, oligonucleotide, biopharmaceutical and vaccine programs., At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We're uniting science, technology and talent to get ahead of disease together.
Find out more: Our approach to R&D. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.