CAR-T Clinical Fellow - Haematology

This role is set within the department of malignant haematology at UCLH with a focus on cellular therapy (including CAR-T) in accordance with JACIE accreditation standards and NHSE guidance. The T-cell Immunotherapy service at UCLH is undergoing significant expansion and the post-holder will be involved in the delivery of (1) licenced/NHSE CAR T-cell products; (2) the academic and commercial CAR T-cell trial portfolio and (3) a portfolio of TCR-transduced T-cell and Tumour Infiltrating Lymphocyte (TIL) therapies for solid tumours which we hope to further cultivate and develop through the appointments.

There will be training in trial design and delivery through involvement in Tumour Management Group meetings for the academic trial portfolio alongside attendance at Site Initiation Visits for new studies. Training regarding the function of apheresis and the stem cell lab will also be provided.

The appointment will be initially for a period of 1 year with the potential for renewal on an annual basis. The roles will provide structured training in cellular therapy and it will be possible for applicants to develop a research project with a view to undertaking an MD/PhD. There will be an honorary contract with the UCL Cancer Institute for the post-holders., Specific responsibilities will include:o Outpatient management of patients receiving CAR-T therapy as well as providing support for patients with complications post-therapyo Liaising with NCCP and clinical trials team to coordinate work-up and care of patients scheduled for CAR-T and other T-cell therapies therapyo Liaising with district general hospitals to assist with cellular therapy patientso Reviewing patients who attend on an emergency basis to the haematology day unito Reviewing patients in the weekly T-cell Immunotherapy clinicso Interaction with lab teams processing translational patient samples and interface with academic trials manufacturing team.

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.

We provide first-class acute and specialist services across eight sites:

University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)

National Hospital for Neurology and Neurosurgery

Royal National ENT and Eastman Dental Hospitals

University College Hospital Grafton Way Building

Royal London Hospital for Integrated Medicine

University College Hospital Macmillan Cancer Centre

The Hospital for Tropical Diseases

University College Hospital at Westmoreland Street

We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.

We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.

£55,329 to £63,152 a year Per annum plus London Weighting (See JD for out-of-hours)