Clinical Research Fellow in Cystic Fibrosis

This post offers an exciting opportunity to work in cystic fibrosis, focusing on cutting-edge diagnostic techniques, with the aim of obtaining a post graduate degree (PhD) from Imperial College London. It is ideally suited for a respiratory (adult or paediatric) trainee wishing to undertake Out of Programme (OOP) training in clinical research with a focus on advanced diagnostics and personalised medicine by developing and validating novel methods such as organoid technology. It could also suit gastroenterology trainees. This has been made possible by a CF Trust-Funded Development Award which includes world experts in CF organoid technology from Utrecht Medical Centre (UMC), Netherlands, and co-investigators from Kings College London, Imperial College London and Kings College Hospital. The successful candidate will also have an opportunity to contribute to our highly successful Clinical Trials Team and experience all aspects of CF care, with its multi-disciplinary team approach., This the predominant role of the post is research. The post holder will be supported towards obtaining a PhD degree from Imperial College London. As outlined above, the post holder will have the opportunity to develop and validate novel techniques, centred around organoid technology, to improve the diagnostic outcomes in CF and 'CF-like' conditions, including bronchiectasis. The role will include writing study protocols, submissions to ethics committees and ultimately completion of the research project, with supervisor support. The post holder will work collaboratively with other scientists from Kings College London and have direct support from experts from UMC, Netherlands.

Royal Brompton Hospital is the largest postgraduate specialist heart and lung centre in the United Kingdom. A fundamental strength of the hospital is close collaboration between the various clinical specialities which cover all aspects of heart and lung disease and collaboration on basic science research with the National Heart and Lung Institute. The hospital enjoys first rate diagnostic and clinical support services, and services are organised into a clinical directorate structure, with each directorate led by a clinical director.

The Royal Brompton Hospital adult and paediatric CF centres are among the largest in Europe with approximately 900 CF patients and 100 CFTR-Related Disorder patients. It has a reputation for high quality clinical care and research. It has a unique national 'Difficult CF Diagnosis' (DCFD) service, using state-of-the art diagnostic techniques including novel genomics and functional tests, including nasal potential difference measurement.

Depending on experience Dependent on ST level