Postdoctoral Research Associate in Translational Biology

As a Postdoctoral Research Associate in Translational Biology you will lead laboratory experiments and the computational analysis and interpretation of data with the goal of discovering biological pathways, patterns and genes that are responsible for the drivers of drug response or resistance in multiple myeloma. You will specifically interrogate multiple Myeloma cell lines and immune cells for studying the mechanism of action of epigenetic therapy in Multiple Myeloma. In partnership with industrial and academic collaborators you will analyse patient derived genomic, immune, pharmacokinetic and pharmacodynamic data to build hypothesis and test them in laboratory models. You will contribute ideas for new research projects, collaborate in the preparation of scientific reports and journal articles and act as a source of information and advice to other members of the group.

You will hold a PhD/DPhil (or near completion) in a biomedical discipline with direct relevance to molecular techniques and assays together with experience to undertake cell based analysis of drug activities. Ability to develop novel assays for testing compounds and their mechanisms based on genetics, OMICs and other assays is essential for success in this project. We are looking for a candidate who would be able to deliver high quality research outputs, as demonstrated by a strong publication record in high profile scientific journals. Familiarity with the existing literature and research in the field of Myeloma or cancer biology together with passion for problem-solving desirable but not essential. Experience in drug related research, strong publication track record and experience of presenting work at meetings and cross-disciplinary collaborative experience are desirable.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Windmill Road, Oxford, OX3 7LD