Postdoctoral Researcher

We have an exciting opportunity to join the Wood and Sanders Groups in the Department of Paediatrics as our Post Doctoral Researcher.
The successful candidate will join Professor Matthew Wood and Professor Stephan Sanders Groups at the Institute of Development and Regenerative Medicine on the Old Road Campus. The Wood and Sanders Groups focus on developing molecular therapies for disorders of the nervous system and muscle. Our objectives include understanding disease biology, identifying and validating therapeutic targets, and developing gene-based nucleic acid therapeutic platforms. The laboratory uses in-vitro and in-vivo models to evaluate these platforms and simultaneously develops advanced delivery technologies to target relevant tissues and cells, such as skeletal muscle, heart, and nervous system. The laboratory has developed novel oligonucleotide and RNA editing therapies for neuromuscular disorders, including Duchenne Muscular Dystrophy (DMD), Myotonic Dystrophy type 1 (DM1), Spinal Muscular Atrophy (SMA) and Spinal and Bulbar Muscular Atrophy (SBMA). The group has also developed extracellular vesicle
nanotechnologies for targeted cell delivery and discovered delivery technologies, including peptide and antibody-based technologies. Research in the laboratory also includes studying fundamental RNA biology and developing RNA-based therapeutic agents and novel technologies for their delivery. The post will be managed by Prof Carlo Rinaldi
You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology.
This position is offered full-time on a fixed-term contract initially until 30.05.25 with the possibility to extend provided further external funding is available

You will have a a PhD, with proven and demonstrable molecular biology skills, including working with iPSCs. You will be able to design the experiments, execute the experiment using various molecular biology techniques, and help analyse the data. You will have highly effective verbal and written communication skills with all level of staff staff and an ability to operate effectively in a demanding research environment.