Research Assistant in Molecular Medicine

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Windmill Road, Oxford, OX3 7LD
We are seeking a Research Assistant to join the Alsaleh Group based in the Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford. Our research uses primary human chondrocytes and fibroblasts in 2D and 3D cell culture systems to investigate age-related changes in senescence and autophagy in the synovium, which may underpin osteoarthritis. This work will be leveraged to support a complementary effort aiming to identify new drug targets and develop new drugs.
As a Research Assistant, you will be following up to validate hits from a genetic CRISPR screen on regulators of autophagy expression. You will ensure records of human tissue samples received and processed are up-to-date and accurate and assist with the analysis of research results. You will also assist with ordering items for the laboratory and ensuring the laboratory is stocked and equipped. There will also be opportunities to represent the research group at external meetings/seminars and contribute to project updates for funders and in writing journal articles.

You will hold a first degree in a biomedical discipline together with relevant laboratory experience. You must also have sufficient specialist knowledge in the discipline to work within our established research programmes, as well as experience of sequencing or imaging of tissues. Excellent communication skills, including the ability to write text that can be published, present data at conferences, and represent the research group at meetings are also essential. Experience of working with human tissues and culture genetics techniques is desirable.