Research Associate (Balasubramanian Group) (Fixed Term)

We are seeking a postdoctoral scientist to work with Professor Sir Shankar Balasubramanian on the chemical biology of nucleic acids and their role in the fundamental mechanisms of cancer. The post will be based in our group at Cancer Research UK's Cambridge Institute (CI) and involves close collaboration with our group based in the University Chemistry Department. The post is available from Autumn 2024. We have a vacancy for a molecular biologist to contribute to our research on genome structure and function. Current projects include elucidating four-stranded nucleic acid structures (G-quadruplexes), their interacting proteins, their mechanisms in relation to gene expression regulation, and their suitability as therapeutic targets and biomarkers of cancer. We also study the structure and function of chemically-modified DNA bases and their epigenetic roles in normal biology and disease. Our interdisciplinary lab innovates and applies methods that include sequencing technologies, genome-targeting and chemical biology. Our ideal candidate will have a capacity for innovation, initiative and creativity to solve biological problems using molecular and cellular strategies. We value good communication skills and an ability to work well in a multi-disciplinary team. This project provides an opportunity for an outstanding individual to make an inspired contribution to the fundamental understanding of genome function. Candidates should have (or be about to receive) a PhD in a relevant discipline. See https://www.balasubramanian.co.uk for further information. Fixed-term: The funds for this post are available for 2 years in the first instance. Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University. We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements. We particularly welcome applications from women and /or candidates from a BME background for this vacancy as they are currently under-represented at this level in our department. Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online. Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter and publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application. Please quote reference SW41419 on your application and in any correspondence about this vacancy. The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Further information

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