Research Fellow

The selected candidate will join a vibrant and internationally recognised research team aimed to understand the disease mechanisms of inherited cardiac conditions. They will undertake research into disease mechanisms of filamin C-associated cardiomyopathy and its translational implications on a Heart Research UK funded project. The successful applicant will work together with colleagues and employ induced pluripotent stem cell derived cardiomyocytes as a cellular model of disease. They will use electrophysiological and molecular biology methods to characterise these cells. For this project, the successful applicant will collaborate closely with clinician scientists from the University of Glasgow. Main Duties

• Perform experiments using tissue and cellular models of cardiomyopathies (this may require working weekends at times)
• Perform detailed analysis and interpretation of data collected through various research methods, including scientific experimentation and literature reviews.
• Apply specialized knowledge in electrophysiological and molecular biology approaches to develop new intellectual understandings in the field
• Analyze, interpret, and present research findings and results in a clear and concise manner, contributing to the field's body of knowledge.
• Disseminate findings from research to specialist and lay audiences (incl. writing scientific publications)
• Contribute to the writing of grant proposals and funding applications to secure resources for ongoing and future research.
• Supervise and provide guidance to students engaged in research work, and mentor PhD students in areas relevant to the project.
• Undertake administrative and management tasks arising from research activities, ensuring project efficiency and compliance
• Address and resolve problems that may impede the achievement of research objectives and adherence to deadlines.
• Contribute to the public understanding and visibility of the discipline through publications, presentations, and outreach activities.
  
  Essential: Possession of a first degree and a PhD (or near to completion) in cell biology, biomedical sciences, genetics, or a closely related field, demonstrating deep expertise in cell biology and electrophysiology
• Essential: Proficient skills in tissue culture of mammalian cells and electrophysical techniques
• Desirable: Knowledge of the cardiovascular system and genetic diseases, experience of single cell patch clamping techniques
• Desirable: Experience of working with induced pluripotent stem cells and their differentiation into cardiac cells.
• Desirable: Proficient skills in the molecular characterisation of disease models, by at least one of: qPCR, Western blotting or confocal microscopy
• High-level analytical capability, with a proven track record of problem-solving in complex research environments.
• Open-minded and team-oriented, with a readiness to work collaboratively in a multidisciplinary research environment.