Scientist III, Research & Development

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), As part of a multidisciplinary team, you will principally be tasked with the primary structural analyses of protein samples provided by internal PDX colleagues, while your unique expertise and experience will enhance the general problem solving and experimental capabilities of the wider department. Protein and protein-associated molecules underpin everything that PDX does, which emphasizes the importance of a strong structural characterisation background for this position. Your scientific knowledge, insight & creativity will allow you to employ experimental resources, and be instrumental in contributing to intelligent design choices and technical solutions. The role will also support other areas of the organisation through communication and scientific expertise to improve existing procedures and to transition prototype technologies into routine clinical use. Role description The primary responsibility of this role is to lead the design, execution, and evaluation of experimental work to meet project goals. This entails being open to new ideas and methods, synthesizing information from diverse sources, and making well-informed decisions both autonomously and collaboratively. This position is based in both the laboratory and office, involving standard proteomic procedures, as well as innovative method development, research, targeted problem-solving, and technology transfer. We are looking for someone who can thrive in a dynamic, fast-paced environment, with a strong motivation to learn and disseminate knowledge. As a professional scientist, you will be expected to actively share ideas and feedback across various functions and provide positive mentorship to fellow scientists in their professional growth. Participation in broader laboratory and departmental tasks is also anticipated., As an experienced team member, you will be expected to showcase a variety of fundamental skills and be open to growth in other areas. The primary role involves leading the operations of a structural characterisation lab supporting the daily operations of a specialist protein manufacturer. Responsibilities include a mix of semi-routine proteomic sample analysis and custom sample structural elucidation. You will own projects from design to implementation and analysis. A motivated approach to mastering scientific techniques and contributing innovative ideas for new product development, process enhancement, and customer solutions is essential.

An academic and/or industrial background in at least one relevant scientific area is essential. For example: biochemistry, biophysics, analytical science or immunology. Candidates with a track record of laboratory-based research and a genuine passion for scientific discovery would be particularly suited to this role. We are a multidisciplinary team, where complementary qualifications or working knowledge in any of the following areas would be welcomed:

• mass spectrometry,
• mathematics,
• statistics,
• physics or chemistry.
The level of this role should meet either one of the following:
• MSc/MA or equivalent UK Level 7 ( with practical research experience)
• PhD/DPhil or equivalent UK Level 8 ( with practical research experience)
Scientific Experience The ideal candidate will have a minimum of 3 years laboratory experience (industrial or academic) and an understanding or practical experience in one or more of the following areas will be advantageous:
• Principle and techniques of mass spectrometry
• Practical experience of hyphenated techniques, specifically LC-ESI-MS, MALDI-TOF
• Informatics experience, specifically in an 'omics field
• Protein biochemistry
• Chromatography
• Protein characterisation techniques (electrophoretic, higher order or similar)
• Protein-protein interaction techniques
• Automated Immunoprecipitation/immunological assays
• Bioconjugation/surface chemistry
• Assay development
• Scientific data analysis
  
  As part of the Thermo Fisher Scientific team, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world's toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
  
  At Thermo Fisher Scientific, each one of our 100,000 extraordinary minds have a unique story to tell. Join us and contribute to our singular mission-enabling our customers to make the world healthier, cleaner and safer. We offer:
• competitive pay,
• annual incentive plan bonus scheme
• healthcare
• company pension
• a range of additional employee benefits.