Senior Locally Employed Doctor (Clinical Research Fellow)

The National Institute of Health and Care Research (NIHR) funds Biomedical Research Centres (BRCs) as experimental medicine centres of excellence via competitive application every five years. Manchester Biomedical Research Centre (BRC) has recently been renewed over five years to provide experimental medicine infrastructure funding across Greater Manchester, Lancashire and South Cumbria.

Manchester BRC drives forward experimental medicine across a range of research themes which are grouped into four clusters: Inflammation, Cancer, High Burden Under Researched Conditions and Disease Complexity as areas where the region has demonstrable strength and which will work collaboratively to improve patient outcomes and embed, build and accelerate personalised health and care for all.

The post will support an MRC Experimental Medicine Grant embedded within the Respiratory theme of the BRC. This grant will assess the effects of disruption of the microbiota with broad-spectrum antibiotics on pulmonary immunity in humans. Pre-clinical data suggest antibiotic use promotes type 2 immunity in the lungs, aligned with epidemiological evidence linking asthma to antibiotic use in humans.,

• To assist with the planning, set up and implementation of the new research studies.


• Manage ethics and regulatory submissions


• Work alongside Study Principal Investigators, assessing all aspects of study feasibility and risk.


• To be aware of and work within the guidelines for biomedical research set out in the Declaration of Helsinki.


• To ensure compliance with the guidelines for Good Clinical Practice as set out in the EU Directive for Clinical Trials.


• To follow standard operating procedures and study protocols.


• Facilitate, organise and carry out patient recruitment


• Identification and recruitment of participants to the relevant research studies


• Confirming if participants are eligible for inclusion into research studies according to the study protocol
  
  MFT is England's largest NHS Trust with a turnover of £2.6bn & is on a different scale than most other NHS Trusts. We're creating an exceptional integrated health & social care system for the 1 million patients who rely on our services every year.


Bringing together 10 hospitals & community services from across Manchester, Trafford & beyond, we champion collaborative working & transformation, encouraging our 28,000 workforce to pursue their most ambitious goals. We set standards that other Trusts seek to emulate so you'll benefit from a scale of opportunity that is nothing short of extraordinary.

We've also created a digitally enabled organisation to improve clinical quality, patient & staff experience, operational effectiveness & driving research and innovation through the introduction of Hive; our brand-new Electronic Patient Record system which we've launched in September 2022.

We're proud to be a major academic Research Centre & Education provider, providing you with a robust infrastructure to encourage and facilitate high-quality research programmes. What's more, we're excited to be embarking on our new Green Plan which will set out how MFT continues to play its part in making healthcare more sustainable.

At MFT, we create and foster a culture of inclusion and belonging, provide equal opportunities for career development that are fair, open and transparent, protecting your health and wellbeing and shaping the future of our organisation together.