Senior Scientist I, Antibody Platform
IMMUNOCORE LTD, Oxford
Senior Scientist I, Antibody Platform
Salary not available. View on company website.
IMMUNOCORE LTD, Oxford
- Full time
- Permanent
- Onsite working
Posted today, 23 Oct | Get your application in now to be one of the first to apply.
Closing date: Closing date not specified
job Ref: 8d143ce699d04cb4a10bad2ba290679b
Full Job Description
- Provide strong scientific and technical expertise in antibody research, including antibody fragments such as scFv and VHH, bispecifics and multi-specifics
- Antibody fragment discovery via in vitro platforms such as phage display, library construction, selection, and screening
- Engineering of antibody fragments, including affinity maturation, format optimisation, and developability approaches
- Identify and work up innovative antibody technologies that will benefit our multi-specific discovery pipeline
- Analyse, interpret and effectively communicate plans and findings at departmental, project, and leadership team meetings, providing go/no go recommendations
- Independently plan, design, and execute experimental projects of diverse scope, trouble-shooting problems and providing recommendations on next steps
- Contribute to peer reviewed publications, patents and international conferences
- Contribute to internal and external collaborations
- Provide technical training to team members where required
- Ensure own work, and work of peers, follow Good Laboratory Practice, and adhere to Immunocore health and safety policies
Strong experience in molecular biology and protein expression and purification techniques e.g. PCR, antibody V-gene cloning, antibody expression & purification in bacterial and/or mammalian systems - Experience in protein biophysical characterisation methods such as SPR or BLI
- Track record of identifying, evaluating, and making recommendations on new technologies to pursue
- Track record of solving scientific problems creatively
- Track record of collaborating and contributing as a project team member
- Effective communication of scientific concepts and findings Desirable
- Experience in engineering and evaluation of multi-specific antibody formats
- Knowledge of biologics drug discovery
- Experienced in use of automation e.g., colony picking, liquid handlers KEY BEHAVIOURAL ATTRIBUTES
- Attention to detail and quality
- Strong organisation skills with ability to plan, prioritise and coordinate work with others
- Strong team player with ability to actively listen and work productively with other team members in a matrix environment
- Ability to communicate clearly to relevant audiences
- Demonstrates innovative thinking Education & Qualifications
- BSc. Or MSc. in protein engineering, biochemistry, molecular biology, or related discipline
- PhD (preferable) in related discipline and at least two years related experience
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits.