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Job offer Microbiology and Immunology: Fully Funded PhD Studentship: Tumour Growth
Salary not available. View on company website.
SWANSEA UNIVERSITY, Abertawe
- Onsite working
- Full time
- Temporary
Posted today, 3 Apr
Job ref: d2ab968c6a2145c7bf73dbf0db9d7a19
Full Job Description
Job Offer
Job: Microbiology and Immunology: Fully Funded PhD Studentship: Tumour Growth
Organisation/Company: Swansea University
Department: Central
Research Field: Computer science
Researcher Profile: First Stage Researcher (R1)
Positions: PhD Positions
Country: United Kingdom
Application Deadline: 14 May 2025 - 12:59 (Europe/London)
Type of Contract: Temporary
Job Status: Full-time
Hours Per Week: 35
Offer Starting Date: 1 Jul 2025
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
Offer Description
Ovarian cancer is the deadliest of all gynaecological cancers (>2000 deaths/year, UK). It is described as a silent killer as most diagnoses occur after it has spread to the peritoneal cavity (metastasis). It is known that peritoneal cells contribute to the growth of metastatic tumours. Previously, it was demonstrated that an immune cell-produced metabolite promotes peritoneal tumour growth. However, a host of interconnected metabolic and immune pathways likely regulate tumour progression.
Identification of these novel mechanisms will provide new targeted therapeutic strategies for ovarian cancer.
The current MRC New Investigator Grant focuses on peritoneal dialysis for kidney disease and aims to add metabolites/drugs to improve this treatment, but this also opens the exciting possibility for using peritoneal dialysis as a tissue-targeted drug delivery tool for metastatic ovarian cancer. This includes utilising existing chemotherapies (e.g. Carboplatin) and targeting new peritoneal-specific mechanisms that promote tumour growth.
Requirements
Research Field: Computer science
Education Level: Undergraduate
Skills/Qualifications:
- IELTS 6.5 Overall (with no individual component below 6.5) or Swansea University recognised equivalent.
Additional Information
Benefits:
- The studentship covers tuition fees and an annual tax-free living stipend in line with UKRI minimum rates (currently £19,237 for 2024/25).
- There is also an additional £1,000 for research expenses.
Eligibility criteria:
Due to funding restrictions, this scholarship is open to applicants eligible to pay tuition fees at the UK rate only, as defined by UKCISA regulations.
Applicants for PhD must normally hold an undergraduate degree at 2.1 level and a master's degree. Alternatively, applicants with a UK first class honours degree (or Non-UK equivalent as defined by Swansea University) not holding a master's degree, will be considered on an individual basis.
Selection process: Please see our website for more information.
Work Location(s)
Number of offers available: 1
Company/Institute: Swansea University
Country: United Kingdom
City: Swansea
Postal Code: SA2 8PP
Contact
State/Province: West Glamorgan
City: Swansea
Street: Singleton Park
Postal Code: SA28PP
E-Mail: l.c.davies@swansea.ac.uk
Phone: +44(0)1792602768
Status: EXPIRED
#s1-Gen
Research Field
Computer science
Education Level
Undergraduate, IELTS 6.5 Overall (with no individual component below 6.5) or Swansea University recognised equivalent., Applicants for PhD must normally hold an undergraduate degree at 2.1 level and a master's degree. Alternatively, applicants with a UK first class honours degree (or Non-UK equivalent as defined by Swansea University) not holding a master's degree, will be considered on an individual basis. See - Country-specific Information for European Applicants 2019 and Country-specific Information for International Applicants 2019.
Ovarian cancer is the deadliest of all gynaecological cancers (>2000 deaths/year, UK). It is described as a silent killer as most diagnoses occur after it has spread to the peritoneal cavity (metastasis). It is known that peritoneal cells contribute to the growth of metastatic tumours. Previously, it was demonstrated that an immune cell-produced metabolite promotes peritoneal tumour growth (https://doi.org/10.1172/jci99169). However, a host of interconnected metabolic and immune pathways likely regulate tumour progression.
Identification of these novel mechanisms will provide new targeted therapeutic strategies for ovarian cancer.
The current MRC New Investigator Grant focuses on peritoneal dialysis for kidney disease and aims to add metabolites/drugs to improve this treatment, but this also opens the exciting possibility for using peritoneal dialysis as a tissue-targeted drug delivery tool for metastatic ovarian cancer. This includes utilising existing chemotherapies (e.g. Carboplatin) and targeting new peritoneal-specific mechanisms that promote tumour growth.
The studentship covers tuition fees and an annual tax-free living stipend in line with UKRI minimum rates (currently £19,237 for 2024/25).
There is also an additional £1,000 for research expenses.
Eligibility criteria
Due to funding restrictions, this scholarship is open to applicants eligible to pay tuition fees at the UK rate only, as defined by UKCISA regulations
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